Inhibition of ATPIF1 Ameliorates Severe Mitochondrial Respiratory Chain Dysfunction in Mammalian Cells

Inhibition of ATPIF1 Ameliorates Severe Mitochondrial Respiratory Chain Dysfunction in Mammalian Cells

Mitochondrial respiratory chain disorders are characterized by loss of electron transport chain (ETC) activity. Although the causes of many such diseases are known, there is a lack of effective therapies. To identify genes that confer resistance to severe ETC dysfunction when inactivated, we perform...

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Bibliographic Details
Main Authors: Chen, Walter W., Mihaylova, Maria M., Snitkin, Harriet, Stasinski, Iwona, Yucel, Burcu, Bayraktar, Erol C., Carette, Jan E., Clish, Clary, Brummelkamp, Thijn R., Sabatini, David M., Birsoy, Kivanc
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/96752
https://orcid.org/0000-0002-7043-5013
https://orcid.org/0000-0002-1446-7256

Internet

http://hdl.handle.net/1721.1/96752
https://orcid.org/0000-0002-7043-5013
https://orcid.org/0000-0002-1446-7256

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