Antibacterial Activity of and Resistance to Small Molecule Inhibitors of the ClpP Peptidase

There is rapidly mounting evidence that intracellular proteases in bacteria are compelling targets for antibacterial drugs. Multiple reports suggest that the human pathogen Mycobacterium tuberculosis and other actinobacteria may be particularly sensitive to small molecules that perturb the activitie...

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Bibliographic Details
Main Authors: Compton, Corey L., Schmitz, Karl R., Sello, Jason K., Sauer, Robert T
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2015
Online Access:http://hdl.handle.net/1721.1/96753
https://orcid.org/0000-0002-9309-8662
https://orcid.org/0000-0002-1719-5399