The Adaptor Protein p66Shc Inhibits mTOR-Dependent Anabolic Metabolism
Adaptor proteins link surface receptors to intracellular signaling pathways and potentially control the way cells respond to nutrient availability. Mice deficient in p66Shc, the most recently evolved isoform of the Shc1 adaptor proteins and a mediator of receptor tyrosine kinase signaling, display r...
Main Authors: | , , , , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
American Association for the Advancement of Science (AAAS)
2015
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Online Access: | http://hdl.handle.net/1721.1/96756 https://orcid.org/0000-0002-0079-4467 https://orcid.org/0000-0002-1446-7256 |