Pd-Catalyzed Nucleophilic Fluorination of Aryl Bromides

On the basis of mechanism-driven reaction design, a Pd-catalyzed nucleophilic fluorination of aryl bromides and iodides has been developed. The method exhibits a broad substrate scope, especially with respect to nitrogen-containing heteroaryl bromides, and proceeds with minimal formation of the corr...

Full description

Bibliographic Details
Main Authors: Lee, Hong Geun, Milner, Phillip John, Buchwald, Stephen Leffler
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2015
Online Access:http://hdl.handle.net/1721.1/96758
https://orcid.org/0000-0003-3875-4775
https://orcid.org/0000-0001-8075-1100