Target specificity of the CRISPR-Cas9 system
The CRISPR-Cas9 system, naturally a defense mechanism in prokaryotes, has been repurposed as an RNA-guided DNA targeting platform. It has been widely used for genome editing and transcriptome modulation, and has shown great promise in correcting mutations in human genetic diseases. Off-target effect...
Egile Nagusiak: | Wu, Xuebing, Kriz, Andrea J., Sharp, Phillip A. |
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Beste egile batzuk: | Massachusetts Institute of Technology. Department of Biology |
Formatua: | Artikulua |
Hizkuntza: | en_US |
Argitaratua: |
Springer-Verlag
2015
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Sarrera elektronikoa: | http://hdl.handle.net/1721.1/96803 https://orcid.org/0000-0003-1465-1691 https://orcid.org/0000-0003-0369-5269 |
Antzeko izenburuak
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Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
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Highly efficient targeted mutagenesis of Drosophila with the CRISPR/Cas9 system.
nork: Bassett, A, et al.
Argitaratua: (2013) -
Highly Efficient Targeted Mutagenesis of Drosophila with the CRISPR/Cas9 System
nork: Bassett, A, et al.
Argitaratua: (2014) -
Highly efficient targeted mutagenesis of Drosophila with the CRISPR/Cas9 system
nork: Bassett, AR, et al.
Argitaratua: (2013)