Target specificity of the CRISPR-Cas9 system

Target specificity of the CRISPR-Cas9 system

The CRISPR-Cas9 system, naturally a defense mechanism in prokaryotes, has been repurposed as an RNA-guided DNA targeting platform. It has been widely used for genome editing and transcriptome modulation, and has shown great promise in correcting mutations in human genetic diseases. Off-target effect...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Wu, Xuebing, Kriz, Andrea J., Sharp, Phillip A.
Beste egile batzuk:	Massachusetts Institute of Technology. Department of Biology
Formatua:	Artikulua
Hizkuntza:	en_US
Argitaratua:	Springer-Verlag 2015
Sarrera elektronikoa:	http://hdl.handle.net/1721.1/96803 https://orcid.org/0000-0003-1465-1691 https://orcid.org/0000-0003-0369-5269

Antzeko izenburuak

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