The Extreme Anterior Domain Is an Essential Craniofacial Organizer Acting through Kinin-Kallikrein Signaling

The Extreme Anterior Domain Is an Essential Craniofacial Organizer Acting through Kinin-Kallikrein Signaling

The extreme anterior domain (EAD) is a conserved embryonic region that includes the presumptive mouth. We show that the Kinin-Kallikrein pathway is active in the EAD and necessary for craniofacial development in Xenopus and zebrafish. The mouth failed to form and neural crest (NC) development and mi...

Full description

Bibliographic Details
Main Authors: Sindelka, Radek, Chen, Justin, Rothman, Alyssa, Dickinson, Amanda J., Jacox, Laura A., Sive, Hazel L.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/96821
https://orcid.org/0000-0002-2634-6689
https://orcid.org/0000-0002-4890-424X
https://orcid.org/0000-0001-6631-0042

Internet

http://hdl.handle.net/1721.1/96821
https://orcid.org/0000-0002-2634-6689
https://orcid.org/0000-0002-4890-424X
https://orcid.org/0000-0001-6631-0042

Similar Items