Bidirectional switch of the valence associated with a hippocampal contextual memory engram

The valence of memories is malleable because of their intrinsic reconstructive property. This property of memory has been used clinically to treat maladaptive behaviours. However, the neuronal mechanisms and brain circuits that enable the switching of the valence of memories remain largely unknown....

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Bibliographic Details
Main Authors: Redondo, Roger L., Kim, Joshua, Liu, Xu, Tonegawa, Susumu, Arons, Autumn, Ramirez Moreno, Steve
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2015
Online Access:http://hdl.handle.net/1721.1/96823
https://orcid.org/0000-0003-2839-8228
https://orcid.org/0000-0002-6697-8330
https://orcid.org/0000-0003-4455-3398