Genome-wide localization of small molecules

Genome-wide localization of small molecules

A vast number of small-molecule ligands, including therapeutic drugs under development and in clinical use, elicit their effects by binding specific proteins associated with the genome. An ability to map the direct interactions of a chemical entity with chromatin genome-wide could provide important...

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Bibliographic Details
Main Authors: Anders, Lars, Guenther, Matthew G., Qi, Jun, Fan, Zi Peng, Marineau, Jason J, Rahl, Peter B, Sigova, Alla A, Smith, William B, Lee, Tong Ihn, Bradner, James E., Young, Richard A., Loven, Jakob
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Nature Publishing Group 2015
Online Access:http://hdl.handle.net/1721.1/96850
https://orcid.org/0000-0001-8855-8647

Internet

http://hdl.handle.net/1721.1/96850
https://orcid.org/0000-0001-8855-8647

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