The Development of Selective Inhibitors of NagZ: Increased Susceptibility of Gram-Negative Bacteria to β-Lactams

The Development of Selective Inhibitors of NagZ: Increased Susceptibility of Gram-Negative Bacteria to β-Lactams

The increasing incidence of inducible chromosomal AmpC β-lactamases within the clinic is a growing concern because these enzymes deactivate a broad range of even the most recently developed β-lactam antibiotics. As a result, new strategies are needed to block the action of this antibiotic resistance...

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Bibliographic Details
Main Authors: Stubbs, Keith A., Bacik, John-Paul, Perley-Robertson, G. Evan, Whitworth, Garrett E., Gloster, Tracey M., Vocadlo, David J., Mark, Brian L.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: Wiley Blackwell 2015
Online Access:http://hdl.handle.net/1721.1/96858

Internet

http://hdl.handle.net/1721.1/96858

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