The Development of Selective Inhibitors of NagZ: Increased Susceptibility of Gram-Negative Bacteria to β-Lactams
The increasing incidence of inducible chromosomal AmpC β-lactamases within the clinic is a growing concern because these enzymes deactivate a broad range of even the most recently developed β-lactam antibiotics. As a result, new strategies are needed to block the action of this antibiotic resistance...
Main Authors: | Stubbs, Keith A., Bacik, John-Paul, Perley-Robertson, G. Evan, Whitworth, Garrett E., Gloster, Tracey M., Vocadlo, David J., Mark, Brian L. |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | en_US |
Published: |
Wiley Blackwell
2015
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Online Access: | http://hdl.handle.net/1721.1/96858 |
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