Synthetic Methods for the Preparation of Platinum Anticancer Complexes

The demonstration in the 1960s that cis-diammine-dichloroplatinum(II), or cisplatin, inhibits cellular division of Escherichia coli led to the subsequent discovery that this simple coordination compound is also an effective antitumor agent in mouse models. Subsequent studies validated cisplatin as a...

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Bibliographic Details
Main Authors: Wilson, Justin J., Lippard, Stephen J.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2015
Online Access:http://hdl.handle.net/1721.1/96862
https://orcid.org/0000-0002-2693-4982