Long-Term Seizure Suppression and Optogenetic Analyses of Synaptic Connectivity in Epileptic Mice with Hippocampal Grafts of GABAergic Interneurons
Studies in rodent epilepsy models suggest that GABAergic interneuron progenitor grafts can reduce hyperexcitability and seizures in temporal lobe epilepsy (TLE). Although integration of the transplanted cells has been proposed as the underlying mechanism for these disease-modifying effects, prior st...
Main Authors: | Henderson, K. W., Gupta, J., Litvina, E., Zheng, X., Van Zandt, M. A., Woods, N., Grund, E., Lin, D., Royston, S., Yanagawa, Y., Aaron, G. B., Naegele, J. R., Tagliatela, Stephanie |
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其他作者: | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
格式: | Article |
語言: | en_US |
出版: |
Society for Neuroscience
2015
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在線閱讀: | http://hdl.handle.net/1721.1/96902 |
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