Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells

Post-transcriptional modification of RNA nucleosides occurs in all living organisms. Pseudouridine, the most abundant modified nucleoside in non-coding RNAs, enhances the function of transfer RNA and ribosomal RNA by stabilizing the RNA structure. Messenger RNAs were not known to contain pseudouridi...

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Bibliographic Details
Main Authors: Carlile, Thomas M., Zinshteyn, Boris, Shin, Hakyung, Bartoli, Kristen Marie, Gilbert, Wendy, Rojas Duran, Maria Fernanda
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2015
Online Access:http://hdl.handle.net/1721.1/96947
https://orcid.org/0000-0002-7699-9354
https://orcid.org/0000-0003-0036-7307
https://orcid.org/0000-0003-2807-9657