Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins

RNA binding proteins of the conserved CUGBP1, Elav-like factor (CELF) family contribute to heart and skeletal muscle development and are implicated in myotonic dystrophy (DM). To understand their genome-wide functions, we analyzed the transcriptome dynamics following induction of CELF1 or CELF2 in a...

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Bibliographic Details
Main Authors: Giudice, Jimena, Treacy, Daniel J., Saxena, Tanvi, Cooper, Thomas A., Ward, Amanda, Cherone, Jennifer Michelle, Freese, Peter Dale, Wang, Thomas, Lambert, Nicole, Burge, Christopher B, Wang, Eric T
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2015
Online Access:http://hdl.handle.net/1721.1/97060
https://orcid.org/0000-0002-0019-5296
https://orcid.org/0000-0001-7256-6845
https://orcid.org/0000-0001-5060-1646