Microfluidic squeezing for intracellular antigen loading in polyclonal B-cells as cellular vaccines
B-cells are promising candidate autologous antigen-presenting cells (APCs) to prime antigen-specific T-cells both in vitro and in vivo. However to date, a significant barrier to utilizing B-cells as APCs is their low capacity for non-specific antigen uptake compared to “professional” APCs such as de...
| Main Authors: | , , , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Nature Publishing Group
2015
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| Online Access: | http://hdl.handle.net/1721.1/97090 https://orcid.org/0000-0003-1833-9822 https://orcid.org/0000-0001-7604-1333 https://orcid.org/0000-0001-7192-580X https://orcid.org/0000-0003-4255-0492 |