Deconstructing transcriptional heterogeneity in pluripotent stem cells

Pluripotent stem cells (PSCs) are capable of dynamic interconversion between distinct substates; however, the regulatory circuits specifying these states and enabling transitions between them are not well understood. Here we set out to characterize transcriptional heterogeneity in mouse PSCs by sing...

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Detalhes bibliográficos
Principais autores: Kumar, Roshan M., Cahan, Patrick, Shalek, Alex K., Satija, Rahul, DaleyKeyser, AJay, Li, Hu, Zhang, Jin, Pardee, Keith, Gennert, David, Trombetta, John J., Ferrante, Thomas C., Regev, Aviv, Daley, George Q., Collins, James J.
Outros Autores: Massachusetts Institute of Technology. Department of Biology
Formato: Artigo
Idioma:en_US
Publicado em: Nature Publishing Group 2015
Acesso em linha:http://hdl.handle.net/1721.1/97189
https://orcid.org/0000-0001-8567-2049