Deconstructing transcriptional heterogeneity in pluripotent stem cells

Pluripotent stem cells (PSCs) are capable of dynamic interconversion between distinct substates; however, the regulatory circuits specifying these states and enabling transitions between them are not well understood. Here we set out to characterize transcriptional heterogeneity in mouse PSCs by sing...

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Bibliographic Details
Main Authors: Kumar, Roshan M., Cahan, Patrick, Shalek, Alex K., Satija, Rahul, DaleyKeyser, AJay, Li, Hu, Zhang, Jin, Pardee, Keith, Gennert, David, Trombetta, John J., Ferrante, Thomas C., Regev, Aviv, Daley, George Q., Collins, James J.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2015
Online Access:http://hdl.handle.net/1721.1/97189
https://orcid.org/0000-0001-8567-2049