Cells change their sensitivity to an EGF morphogen gradient to control EGF-induced gene expression
How cells in developing organisms interpret the quantitative information contained in morphogen gradients is an open question. Here we address this question using a novel integrative approach that combines quantitative measurements of morphogen-induced gene expression at single-mRNA resolution with...
Main Authors: | Kienle, Simone, Huelsz-Prince, Guizela, Barkoulas, Michalis, van Oudenaarden, Alexander, Van Zon, Jeroen Sebastiaan |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2015
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Online Access: | http://hdl.handle.net/1721.1/97210 |
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