A load driver device for engineering modularity in biological networks

The behavior of gene modules in complex synthetic circuits is often unpredictable. After joining modules to create a circuit, downstream elements (such as binding sites for a regulatory protein) apply a load to upstream modules that can negatively affect circuit function. Here we devised a genetic d...

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Bibliographic Details
Main Authors: Mishra, Deepak, Lin, Allen, Del Vecchio, Domitilla, Weiss, Ron, Rivera, Phillip M.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2015
Online Access:http://hdl.handle.net/1721.1/97410
https://orcid.org/0000-0003-0396-2443
https://orcid.org/0000-0002-2682-9699
https://orcid.org/0000-0001-6472-8576