Trade-offs between retroactivity and noise in connected transcriptional components

At the interconnection of two gene transcriptional components in a biomolecular network, the noise in the downstream component can be reduced by increasing its gene copy number. However, this method of reducing noise increases the load applied to the upstream system, called retroactivity, thereby ca...

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Bibliographic Details
Main Authors: Del Vecchio, Domitilla, Herath, Narmada K.
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Format: Article
Language:en_US
Published: 2015
Online Access:http://hdl.handle.net/1721.1/97415
https://orcid.org/0000-0003-2194-3051
https://orcid.org/0000-0001-6472-8576