Limitations and trade-offs in gene expression due to competition for shared cellular resources

Gene circuits share transcriptional and translational resources in the cell. The fact that these common resources are available only in limited amounts leads to unexpected couplings in protein expressions. As a result, our predictive ability of describing the behavior of gene circuits is limited. In...

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书目详细资料
Main Authors: Gyorgy, Andras, Del Vecchio, Domitilla
其他作者: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
格式: 文件
语言:en_US
出版: Institute of Electrical and Electronics Engineers (IEEE) 2015
在线阅读:http://hdl.handle.net/1721.1/97416
https://orcid.org/0000-0001-6472-8576
https://orcid.org/0000-0002-4784-3772