Limitations and trade-offs in gene expression due to competition for shared cellular resources
Gene circuits share transcriptional and translational resources in the cell. The fact that these common resources are available only in limited amounts leads to unexpected couplings in protein expressions. As a result, our predictive ability of describing the behavior of gene circuits is limited. In...
| Main Authors: | , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Institute of Electrical and Electronics Engineers (IEEE)
2015
|
| Online Access: | http://hdl.handle.net/1721.1/97416 https://orcid.org/0000-0001-6472-8576 https://orcid.org/0000-0002-4784-3772 |