Retroactivity attenuation through signal transduction cascades

This paper considers the problem of attenuating retroactivity, that is, the effect of loads in biological networks and demonstrates that signal transduction cascades incorporating phosphotransfer modules have remarkable retroactivity attenuation ability. Uncovering the biological mechanisms for retr...

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Bibliographic Details
Main Authors: Rivera, Phillip M., Del Vecchio, Domitilla
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:en_US
Published: Institute of Electrical and Electronics Engineers (IEEE) 2015
Online Access:http://hdl.handle.net/1721.1/97417
https://orcid.org/0000-0001-6472-8576