Retroactivity attenuation through signal transduction cascades
This paper considers the problem of attenuating retroactivity, that is, the effect of loads in biological networks and demonstrates that signal transduction cascades incorporating phosphotransfer modules have remarkable retroactivity attenuation ability. Uncovering the biological mechanisms for retr...
Main Authors: | Rivera, Phillip M., Del Vecchio, Domitilla |
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Other Authors: | Massachusetts Institute of Technology. Department of Mechanical Engineering |
Format: | Article |
Language: | en_US |
Published: |
Institute of Electrical and Electronics Engineers (IEEE)
2015
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Online Access: | http://hdl.handle.net/1721.1/97417 https://orcid.org/0000-0001-6472-8576 |
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