Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo

Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo

Malaria remains a major global health problem. Emerging resistance to existing antimalarial drugs drives the search for new antimalarials, and protein translation is a promising pathway to target. Here we explore the potential of the aminoacyl-tRNA synthetase (ARS) family as a source of antimalarial...

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Bibliographic Details
Main Authors: Camacho, Noelia, Tor, Anna, Wilkinson, Barrie, Moss, Steven, Mirando, Adam C., Francklyn, Christopher S., Royo, Miriam, Novoa Pardo, Eva Maria, Marin-Garcia, Patricia, Axcarate, Isabel G., Bautista, Jose M., Varon, Sonia, Cortes, Alfred, Ribas de Pouplana, Lluis
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2015
Online Access:http://hdl.handle.net/1721.1/97421
https://orcid.org/0000-0002-9367-6311

Internet

http://hdl.handle.net/1721.1/97421
https://orcid.org/0000-0002-9367-6311

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