Insights into the Human Glycan Receptor Conformation of 1918 Pandemic Hemagglutinin–Glycan Complexes Derived from Nuclear Magnetic Resonance and Molecular Dynamics Studies

Insights into the Human Glycan Receptor Conformation of 1918 Pandemic Hemagglutinin–Glycan Complexes Derived from Nuclear Magnetic Resonance and Molecular Dynamics Studies

The glycan receptor binding and specificity of influenza A viral hemagglutinin (HA) are critical for virus infection and transmission in humans. However, ambiguities in the interpretation of the receptor binding specificity of hemagglutinin from human- and avian-adapted viruses have prevented an und...

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Bibliographic Details
Main Authors: Elli, Stefano, Macchi, Eleonora, Rudd, Timothy R., Raman, Rahul, Sassaki, Guillherme, Viswanathan, Karthik, Yates, Edwin A., Naggi, Annamaria, Torri, Giangiacomo, Sasisekharan, Ram, Guerrini, Marco, Shriver, Zachary H.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2015
Online Access:http://hdl.handle.net/1721.1/97481
https://orcid.org/0000-0002-1288-9965
https://orcid.org/0000-0001-9344-0205
https://orcid.org/0000-0002-2085-7840

Internet

http://hdl.handle.net/1721.1/97481
https://orcid.org/0000-0002-1288-9965
https://orcid.org/0000-0001-9344-0205
https://orcid.org/0000-0002-2085-7840

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