A Convergent Synthetic Platform for Single-Nanoparticle Combination Cancer Therapy: Ratiometric Loading and Controlled Release of Cisplatin, Doxorubicin, and Camptothecin

The synthesis of polymer therapeutics capable of controlled loading and synchronized release of multiple therapeutic agents remains a formidable challenge in drug delivery and synthetic polymer chemistry. Herein, we report the synthesis of polymer nanoparticles (NPs) that carry precise molar ratios...

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Bibliographic Details
Main Authors: Liao, Longyan, Liu, Jenny, Morton, Stephen Winford, Hammond, Paula T., Johnson, Jeremiah A., Dreaden, Erik Christopher, Shopsowitz, Kevin
Other Authors: Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2015
Online Access:http://hdl.handle.net/1721.1/97487
https://orcid.org/0000-0002-4954-8443
https://orcid.org/0000-0003-3988-0837
https://orcid.org/0000-0002-8482-9996
https://orcid.org/0000-0001-9157-6491