A Convergent Synthetic Platform for Single-Nanoparticle Combination Cancer Therapy: Ratiometric Loading and Controlled Release of Cisplatin, Doxorubicin, and Camptothecin
The synthesis of polymer therapeutics capable of controlled loading and synchronized release of multiple therapeutic agents remains a formidable challenge in drug delivery and synthetic polymer chemistry. Herein, we report the synthesis of polymer nanoparticles (NPs) that carry precise molar ratios...
Main Authors: | Liao, Longyan, Liu, Jenny, Morton, Stephen Winford, Hammond, Paula T., Johnson, Jeremiah A., Dreaden, Erik Christopher, Shopsowitz, Kevin |
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Other Authors: | Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society (ACS)
2015
|
Online Access: | http://hdl.handle.net/1721.1/97487 https://orcid.org/0000-0002-4954-8443 https://orcid.org/0000-0003-3988-0837 https://orcid.org/0000-0002-8482-9996 https://orcid.org/0000-0001-9157-6491 |
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