Enterobactin-Mediated Delivery of β-Lactam Antibiotics Enhances Antibacterial Activity against Pathogenic Escherichia coli
The design, synthesis, and characterization of enterobactin–antibiotic conjugates, hereafter Ent-Amp/Amx, where the β-lactam antibiotics ampicillin (Amp) and amoxicillin (Amx) are linked to a monofunctionalized enterobactin scaffold via a stable poly(ethylene glycol) linker are reported. Under condi...
Main Authors: | , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society (ACS)
2015
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Online Access: | http://hdl.handle.net/1721.1/97501 https://orcid.org/0000-0002-6153-8803 |