Enterobactin-Mediated Delivery of β-Lactam Antibiotics Enhances Antibacterial Activity against Pathogenic Escherichia coli

Enterobactin-Mediated Delivery of β-Lactam Antibiotics Enhances Antibacterial Activity against Pathogenic Escherichia coli

The design, synthesis, and characterization of enterobactin–antibiotic conjugates, hereafter Ent-Amp/Amx, where the β-lactam antibiotics ampicillin (Amp) and amoxicillin (Amx) are linked to a monofunctionalized enterobactin scaffold via a stable poly(ethylene glycol) linker are reported. Under condi...

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Bibliographic Details
Main Authors:	Zheng, Tengfei, Nolan, Elizabeth M.
Other Authors:	Massachusetts Institute of Technology. Department of Chemistry
Format:	Article
Language:	en_US
Published:	American Chemical Society (ACS) 2015
Online Access:	http://hdl.handle.net/1721.1/97501 https://orcid.org/0000-0002-6153-8803

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