Systematic identification of signaling pathways with potential to confer anticancer drug resistance
Cancer cells can activate diverse signaling pathways to evade the cytotoxic action of drugs. We created and screened a library of barcoded pathway-activating mutant complementary DNAs to identify those that enhanced the survival of cancer cells in the presence of 13 clinically relevant, targeted the...
Main Authors: | , , , , , , , , , , , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
American Association for the Advancement of Science (AAAS)
2015
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Online Access: | http://hdl.handle.net/1721.1/97538 https://orcid.org/0000-0002-4227-5163 https://orcid.org/0000-0002-1446-7256 |