Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

Background Cancers arise from multiple acquired mutations, which presumably occur over many years. Early stages in cancer development might be present years before cancers become clinically apparent. Methods We analyzed data from whole-exome sequencing of DNA in peripheral-blood cells from 12,380...

Повний опис

Бібліографічні деталі
Автори: Genovese, Giulio, Kahler, Anna K., Handsaker, Robert E., Lindberg, Johan, Rose, Samuel A., Bakhoum, Samuel F., Chambert, Kimberly, Mick, Eran, Neale, Benjamin M., Fromer, Menachem, Purcell, Shaun M., Svantesson, Oscar, Landen, Mikael, Hoglund, Martin, Lehmann, Soren, Gabriel, Stacey B., Moran, Jennifer L., Sullivan, Patrick F., Sklar, Pamela, Gronberg, Henrik, Hultman, Christina M., McCarroll, Steven A., Lander, Eric Steven
Інші автори: Massachusetts Institute of Technology. Department of Biology
Формат: Стаття
Мова:en_US
Опубліковано: New England Journal of Medicine 2015
Онлайн доступ:http://hdl.handle.net/1721.1/97546

Інтернет

http://hdl.handle.net/1721.1/97546

Схожі ресурси