Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

Background Cancers arise from multiple acquired mutations, which presumably occur over many years. Early stages in cancer development might be present years before cancers become clinically apparent. Methods We analyzed data from whole-exome sequencing of DNA in peripheral-blood cells from 12,380...

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Bibliographic Details
Main Authors: Genovese, Giulio, Kahler, Anna K., Handsaker, Robert E., Lindberg, Johan, Rose, Samuel A., Bakhoum, Samuel F., Chambert, Kimberly, Mick, Eran, Neale, Benjamin M., Fromer, Menachem, Purcell, Shaun M., Svantesson, Oscar, Landen, Mikael, Hoglund, Martin, Lehmann, Soren, Gabriel, Stacey B., Moran, Jennifer L., Sullivan, Patrick F., Sklar, Pamela, Gronberg, Henrik, Hultman, Christina M., McCarroll, Steven A., Lander, Eric Steven
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: New England Journal of Medicine 2015
Online Access:http://hdl.handle.net/1721.1/97546

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http://hdl.handle.net/1721.1/97546

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