SIRT1-FOXO3a Regulate Cocaine Actions in the Nucleus Accumbens

SIRT1-FOXO3a Regulate Cocaine Actions in the Nucleus Accumbens

Previous studies have shown that chronic cocaine administration induces SIRT1, a Class III histone deacetylase, in the nucleus accumbens (NAc), a key brain reward region, and that such induction influences the gene regulation and place conditioning effects of cocaine. To determine the mechanisms by...

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Bibliographic Details
Main Authors: Ferguson, Deveroux, Shao, Ningyi, Heller, Elizabeth, Feng, Jian, Neve, Rachael L., Kim, Hee-Dae, Call, Tanessa, Magazu, Samantha, Shen, Li, Nestler, Eric J.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Society for Neuroscience 2015
Online Access:http://hdl.handle.net/1721.1/98034
https://orcid.org/0000-0002-3854-5968

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http://hdl.handle.net/1721.1/98034
https://orcid.org/0000-0002-3854-5968

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