Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome

Mutations in ESCO2, one of two establishment of cohesion factors necessary for proper sister chromatid cohesion (SCC), cause a spectrum of developmental defects in the autosomal-recessive disorder Roberts syndrome (RBS), warranting in vivo analysis of the consequence of cohesion dysfunction. Through...

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Bibliographic Details
Main Authors: Percival, Stefanie M., Thomas, Holly R., Amsterdam, Adam, Carroll, Andrew J., Lees, Jacqueline, Yost, H. Joseph, Parant, John M.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Company of Biologists 2015
Online Access:http://hdl.handle.net/1721.1/98099
https://orcid.org/0000-0001-9451-2194