Loss of Melanopsin Photoreception and Antagonism of the Histamine H3 Receptor by Ciproxifan Inhibit Light-Induced Sleep in Mice

Light has direct effects on sleep and wakefulness causing arousal in diurnal animals and sleep in nocturnal animals. In the present study, we assessed the modulation of light-induced sleep by melanopsin and the histaminergic system by exposing mice to millisecond light flashes and continuous light r...

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Bibliographic Details
Main Authors: Muindi, Fanuel, Colas, Damien, Ikeme, Jesse, Ruby, Norman F., Heller, H. Craig
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Public Library of Science 2015
Online Access:http://hdl.handle.net/1721.1/98135
https://orcid.org/0000-0002-1998-1449