Islet Oxygen Consumption Rate (OCR) Dose Predicts Insulin Independence in Clinical Islet Autotransplantation

Background Reliable in vitro islet quality assessment assays that can be performed routinely, prospectively, and are able to predict clinical transplant outcomes are needed. In this paper we present data on the utility of an assay based on cellular oxygen consumption rate (OCR) in predicting clinic...

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Bibliographic Details
Main Authors: Papas, Klearchos K., Bellin, Melena D., Sutherland, David E. R., Suszynski, Thomas M., Kitzmann, Jennifer P., Avgoustiniatos, Efstathios S., Gruessner, Angelika C., Mueller, Kathryn R., Beilman, Gregory J., Balamurugan, Appakalai N., Loganathan, Gopalakrishnan, Colton, Clark K., Koulmanda, Maria, Weir, Gordon C., Wilhelm, Josh J., Qian, Dajun, Niland, Joyce C., Hering, Bernhard J.
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Public Library of Science 2015
Online Access:http://hdl.handle.net/1721.1/98167
https://orcid.org/0000-0001-8777-9632