Translocation of Non-Canonical Polypeptides into Cells Using Protective Antigen
A variety of pathogenic bacteria infect host eukaryotic cells using protein toxins, which enter the cytosol and exert their cytotoxic effects. Anthrax lethal toxin, for example, utilizes the membrane-spanning translocase, protective antigen (PA) pore, to deliver the protein toxin lethal factor (LF)...
Main Authors: | , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2015
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Online Access: | http://hdl.handle.net/1721.1/98438 https://orcid.org/0000-0003-2659-7012 |