Context influences on TALE–DNA binding revealed by quantitative profiling

Transcription activator-like effector (TALE) proteins recognize DNA using a seemingly simple DNA-binding code, which makes them attractive for use in genome engineering technologies that require precise targeting. Although this code is used successfully to design TALEs to target specific sequences,...

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Bibliographic Details
Main Authors: Rogers, Julia M., Reyon, Deepak, Sander, Jeffry D., Kellis, Manolis, Joung, J. Keith, Bulyk, Martha L., Barrera, Luis Alberto
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Nature Publishing Group 2015
Online Access:http://hdl.handle.net/1721.1/98478
https://orcid.org/0000-0002-4472-4209