iWRAP: An Interface Threading Approach with Application to Prediction of Cancer-Related Protein–Protein Interactions
Current homology modeling methods for predicting protein–protein interactions (PPIs) have difficulty in the “twilight zone” (< 40%) of sequence identities. Threading methods extend coverage further into the twilight zone by aligning primary sequences for a pair of proteins to a best-fit template...
Main Authors: | , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2015
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Online Access: | http://hdl.handle.net/1721.1/98591 https://orcid.org/0000-0003-2598-3552 https://orcid.org/0000-0002-2724-7228 |