Predicting effective microRNA target sites in mammalian mRNAs

MicroRNA targets are often recognized through pairing between the miRNA seed region and complementary sites within target mRNAs, but not all of these canonical sites are equally effective, and both computational and in vivo UV-crosslinking approaches suggest that many mRNAs are targeted through non-...

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Bibliographic Details
Main Authors: Agarwal, Vikram, Bell, George W, Nam, Jin-Wu, Bartel, David
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: eLife Sciences Publications, Ltd. 2015
Online Access:http://hdl.handle.net/1721.1/99103
https://orcid.org/0000-0001-8148-952X
https://orcid.org/0000-0002-3872-2856