Predicting effective microRNA target sites in mammalian mRNAs
MicroRNA targets are often recognized through pairing between the miRNA seed region and complementary sites within target mRNAs, but not all of these canonical sites are equally effective, and both computational and in vivo UV-crosslinking approaches suggest that many mRNAs are targeted through non-...
Main Authors: | Agarwal, Vikram, Bell, George W, Nam, Jin-Wu, Bartel, David |
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Other Authors: | Massachusetts Institute of Technology. Computational and Systems Biology Program |
Format: | Article |
Language: | en_US |
Published: |
eLife Sciences Publications, Ltd.
2015
|
Online Access: | http://hdl.handle.net/1721.1/99103 https://orcid.org/0000-0001-8148-952X https://orcid.org/0000-0002-3872-2856 |
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