Determinants of Homodimerization Specificity in Histidine Kinases

Two-component signal transduction pathways consisting of a histidine kinase and a response regulator are used by prokaryotes to respond to diverse environmental and intracellular stimuli. Most species encode numerous paralogous histidine kinases that exhibit significant structural similarity. Yet in...

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Bibliographic Details
Main Authors: Ashenberg, Orr, Rozen-Gagnon, Kathryn, Keating, Amy E., Laub, Michael T
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/99134
https://orcid.org/0000-0002-8288-7607
https://orcid.org/0000-0003-4074-8980