Proteasomal regulation of the mutagenic translesion DNA polymerase, Saccharomyces cerevisiae Rev1
Translesion DNA synthesis (TLS) functions as a tolerance mechanism for DNA damage at a potentially mutagenic cost. Three TLS polymerases (Pols) function to bypass DNA damage in Saccharomyces cerevisiae: Rev1, Pol ζ, a heterodimer of the Rev3 and Rev7 proteins, and Pol η (Rad30). Our lab has shown th...
Main Authors: | , |
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Format: | Article |
Language: | en_US |
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Elsevier
2015
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Online Access: | http://hdl.handle.net/1721.1/99179 https://orcid.org/0000-0002-4647-4282 https://orcid.org/0000-0001-7243-8261 |