Directing human embryonic stem cell differentiation by non-viral delivery of siRNA in 3D culture

Human embryonic stem cells (hESCs) hold great potential as a resource for regenerative medicine. Before achieving therapeutic relevancy, methods must be developed to control stem cell differentiation. It is clear that stem cells can respond to genetic signals, such as those imparted by nucleic acids...

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Bibliographic Details
Main Authors: Lytton-Jean, Abigail K. R., Deiorio-Haggar, Kaila, Bellan, Leon M., Karagiannis, Emmanouil, Anderson, Daniel Griffith, Zoldan, Janeta, Langer, Robert S
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/99182
https://orcid.org/0000-0003-0131-6552
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0003-4255-0492