28S rRNA is inducibly pseudouridylated by the mTOR pathway translational control in CHO cell cultures
The mTOR pathway is a conserved master regulator of translational activity that influences the fate of industrially relevant CHO cell cultures, yet its molecular mechanisms remain unclear. Interestingly, rapamycin specific inhibition of the mTOR pathway in CHO cells was found to down-regulate the sm...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Elsevier
2015
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| Online Access: | http://hdl.handle.net/1721.1/99335 https://orcid.org/0000-0003-0011-3067 https://orcid.org/0000-0001-9920-2080 |