An automated Fpg-based FADU method for the detection of oxidative DNA lesions and screening of antioxidants

The oxidation of guanine to 8-oxo-2′-deoxyguanosine (8-oxo-dG) is one of the most abundant and best studied oxidative DNA lesions and is commonly used as a biomarker for oxidative stress. Over the last decades, various methods for the detection of DNA oxidation products have been established and opt...

Full description

Bibliographic Details
Main Authors: Moreno-Villanueva, Maria, Fischbach, Arthur, Martello, Rita, Dedon, Peter C., Ullrich, Volker, Mangerich, Aswin, Muller, Nathalie, Kienhofer, Joachim, Burkle, Alexander
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/99338
https://orcid.org/0000-0002-5811-6853
https://orcid.org/0000-0003-0011-3067