An automated Fpg-based FADU method for the detection of oxidative DNA lesions and screening of antioxidants
The oxidation of guanine to 8-oxo-2′-deoxyguanosine (8-oxo-dG) is one of the most abundant and best studied oxidative DNA lesions and is commonly used as a biomarker for oxidative stress. Over the last decades, various methods for the detection of DNA oxidation products have been established and opt...
Main Authors: | Moreno-Villanueva, Maria, Fischbach, Arthur, Martello, Rita, Dedon, Peter C., Ullrich, Volker, Mangerich, Aswin, Muller, Nathalie, Kienhofer, Joachim, Burkle, Alexander |
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Other Authors: | Massachusetts Institute of Technology. Center for Environmental Health Sciences |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2015
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Online Access: | http://hdl.handle.net/1721.1/99338 https://orcid.org/0000-0002-5811-6853 https://orcid.org/0000-0003-0011-3067 |
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