Colitis and Colon Cancer in WASP-Deficient Mice Require Helicobacter Spp.

Colitis and Colon Cancer in WASP-Deficient Mice Require Helicobacter Spp.

Background: Wiskott–Aldrich syndrome protein–deficient patients and mice are immunodeficient and can develop inflammatory bowel disease. The intestinal microbiome is critical to the development of colitis in most animal models, in which Helicobacter spp. have been implicated in disease pathogenesis....

Full description

Bibliographic Details
Main Authors: Nguyen, Deanna D., Goettel, Jeremy A., Eston, Michelle A., Mobley, Melissa W., Taylor, Nancy S., McCabe, Amanda F., Marin, Romela, Snapper, Scott B., Fox, James G., Muthupalani, Sureshkumar
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Lippincott Williams & Wilkins 2015
Online Access:http://hdl.handle.net/1721.1/99369
https://orcid.org/0000-0001-9307-6116

Internet

http://hdl.handle.net/1721.1/99369
https://orcid.org/0000-0001-9307-6116

Similar Items