Effect of molecular weight of amine end-modified poly(β-amino ester)s on gene delivery efficiency and toxicity
Amine end-modified poly(β-amino ester)s (PBAEs) have generated interest as efficient, biodegradable polymeric carriers for plasmid DNA (pDNA). For cationic, non-degradable polymers, such as polyethylenimine (PEI), the polymer molecular weight (MW) and molecular weight distribution (MWD) significantl...
Main Authors: | , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2015
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Online Access: | http://hdl.handle.net/1721.1/99394 https://orcid.org/0000-0001-5629-4798 https://orcid.org/0000-0003-4255-0492 |