Transport and binding of tumor necrosis factor-α in articular cartilage depend on its quaternary structure
The effect of tumor necrosis factor-α (TNFα) on cartilage matrix degradation is mediated by its transport and binding within the extracellular matrix (ECM) of the tissue, which mediates availability to cell receptors. Since the bioactive form of TNFα is a homotrimer of monomeric subunits, conversion...
| Հիմնական հեղինակներ: | , , , , |
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| Այլ հեղինակներ: | |
| Ձևաչափ: | Հոդված |
| Լեզու: | en_US |
| Հրապարակվել է: |
Elsevier
2015
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| Առցանց հասանելիություն: | http://hdl.handle.net/1721.1/99417 https://orcid.org/0000-0002-4942-3456 |