A Small Molecule That Binds and Inhibits the ETV1 Transcription Factor Oncoprotein

A Small Molecule That Binds and Inhibits the ETV1 Transcription Factor Oncoprotein

Members of the ETS transcription factor family have been implicated in several cancers, where they are often dysregulated by genomic derangement. ETS variant 1 (ETV1) is an ETS factor gene that undergoes chromosomal translocation in prostate cancers and Ewing sarcomas, amplification in melanomas, an...

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Bibliographic Details
Main Authors: Pop, Marius S., Stransky, Nicolas, Garvie, Colin W., Theurillat, Jean-Philippe, Hartman, Emily C., Lewis, Timothy A., Zhong, Cheng, Culyba, Elizabeth K., Lin, Fallon, Daniels, Douglas S., Pagliarini, Raymond, Ronco, Lucienne, Koehler, Angela Nicole, Garraway, Levi A.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Association for Cancer Research 2015
Online Access:http://hdl.handle.net/1721.1/99462

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http://hdl.handle.net/1721.1/99462

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